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Posted: May 21st, 2024
Personalised cancer treatment – known markers and what they mean for treatment
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Known markers and what they mean for treatment
Diagnostic and prognostic markers
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Personalised, targeted and hormonal treatments all depend on genetic mutations that can be identified in cancer cells to be effective. These mutations are sometimes referred to as “markers”. The markers can manifest through over-expression, lack of expression or mutated expression of specific proteins.
Some markers can be targeted using specific treatments whereas some can act as measurements for disease diagnosis, prognosis and treatment response.
The genes listed below have all been associated in cancer, the majority of which can also be treated.
Known marker Is My Privacy Protected?100%! We encrypt everything—your details stay secret. Papers are custom, original, and yours alone, so no one will ever know you used us. |
Cancers they’re associated with / may benefit from targeted therapy |
Related treatment/response to treatment |
ALK[EB1] – anaplastic lymphoma kinase (*) |
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AR – androgen receptor Is AI Involved in Writing?Nope—all human, all the time. Our writers are pros with real degrees, crafting unique papers with expertise AI can’t replicate, checked for originality. |
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BRAF – v-raf murine sarcoma viral oncogene homolog B1 |
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BRCA1 – breast cancer susceptibility gene 1 |
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BRCA2 – breast cancer susceptibility gene 2 |
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c-Kit/CD117/SCFR – mast stem cell factor receptor (*) Why Are You the Best for Research?Our writers are degree-holding pros who tackle any topic with skill. We ensure quality with top tools and offer revisions—perfect papers, even under pressure. |
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c-MET/HGFR – mesenchymal epithelial transition factor/hepatocyte growth factor receptor |
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COX-2/PTGS2 – cyclooxygenase-2/ prostaglandin-endoperoxide synthase-2 |
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EGFR/ErbB-1/HER1 – epidermal growth factor receptor (*) |
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ER – oestrogen receptor (*) Who Writes My Assignments?Experts with degrees—many rocking Master’s or higher—who’ve crushed our rigorous tests in their fields and academic writing. They’re student-savvy pros, ready to nail your essay with precision, blending teamwork with you to match your vision perfectly. Whether it’s a tricky topic or a tight deadline, they’ve got the skills to make it shine. |
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ERCC1 – excision repair cross-complementation group 1 |
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HER2/HER2neu/ErbB-2 – human epidermal growth factor receptor 2 (*) |
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KRAS – Kirsten murine sarcoma virus (*) |
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MGMT – O-6-methylguanine-DNA methyltransferase Will My Paper Be Unique?Guaranteed—100%! We write every piece from scratch—no AI, no copying—just fresh, well-researched work with proper citations, crafted by real experts. You can grab a plagiarism report to see it’s 95%+ original, giving you total peace of mind it’s one-of-a-kind and ready to impress. |
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MRP1 – multidrug resistance-associated protein 1 |
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PGP – p-glycoprotein |
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PIK3CAα – phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
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PR – progesterone receptor (*) Can You Use Any Citation Format?Yep—APA, Chicago, Harvard, MLA, Turabian, you name it! Our writers customize every detail to fit your assignment’s needs, ensuring it meets academic standards down to the last footnote or bibliography entry. They’re pros at making your paper look sharp and compliant, no matter the style guide. |
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PTEN – phosphatase and tensin homolog |
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RRM1– ribonucleotide reductase subunit M1 |
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SPARC – secreted protein acidic rich in cysteine |
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TLE3 – transducin-like enhancer of split Can I Change My Order Details?For sure—you’re not locked in! Chat with your writer anytime through our handy system to update instructions, tweak the focus, or toss in new specifics, and they’ll adjust on the fly, even if they’re mid-draft. It’s all about keeping your paper exactly how you want it, hassle-free. |
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TOPO2α – topoisomerase IIα |
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TS – thymidylate synthetase |
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TUBB3 – Class III -tubulin |
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(*) – Targetable genes and proteins that can also be measured to determine treatment response, cancer diagnosis and prognosis.
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The following markers are all related to diagnosis, prognosis and treatment progress.
Known marker |
Associated cancer |
Role How Quick Can You Write?Need it fast? We can whip up a top-quality paper in 24 hours—fully researched and polished, no corners cut. Just pick your deadline when you order, and we’ll hustle to make it happen, even for those nail-biting, last-minute turnarounds you didn’t see coming. |
α (alpha)-fetoprotein |
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Germ cell tumour staging, prognosis, response to treatment Liver cancer diagnosis, response to treatment |
β (beta)-2-microglobulin |
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Prognosis, response to treatment Can You Handle Tough Topics?Absolutely—bring it on! Our writers, many with advanced degrees like Master’s or PhDs, thrive on challenges and dive deep into any subject, from obscure history to cutting-edge science. They’ll craft a standout paper with thorough research and clear writing, tailored to wow your professor. |
β (beta)-human chorionic gonadotropin (β-hCG) |
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Staging, prognosis, response to treatment |
BCR-ABL fusion gene |
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Diagnosis, disease status monitoring |
BRAF (mutation V600E) How Do You Match Professor Expectations?We follow your rubric to a T—structure, evidence, tone. Editors refine it, ensuring it’s polished and ready to impress your prof. |
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Response to targeted treatment |
CA15-3/CA27.29 |
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Treatment success, disease recurrence |
CA19-9 How Do You Edit My Work?Send us your draft and goals—our editors enhance clarity, fix errors, and keep your style. You’ll get a pro-level paper fast. |
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Treatment success |
CA-125 |
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Diagnosis, treatment response, disease recurrence |
Calcitonin |
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Diagnosis, treatment success, disease recurrence Can You Brainstorm Topics?Yep! We’ll suggest ideas tailored to your field—engaging and manageable. Pick one, and we’ll build it into a killer paper. |
Carcinoembryonic antigen (CEA) |
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Breast cancer recurrence, treatment response Colorectal disease advance |
CD20 |
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Response to targeted treatment |
Chromogranin A (CgA) |
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Diagnosis, treatment response, disease recurrence Do You Offer Fast Edits?Yes! Need a quick fix? Our editors can polish your paper in hours—perfect for tight deadlines and top grades. |
Chromosomes 3, 7, 17, 9p21 |
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Disease recurrence |
Cytokeratin fragments 21-1 |
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Disease recurrence |
Fibrin/fibrinogen |
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Treatment response Can You Start With an Outline?Sure! We’ll sketch an outline for your approval first, ensuring the paper’s direction is spot-on before we write. |
Human epididymis protein 4 (HE4) |
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Disease progression, disease recurrence |
Immunoglobulins (antibodies) |
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Diagnosis, treatment response, disease recurrence |
Lactate dehydrogenase |
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Staging, prognosis, treatment response |
Nuclear matrix protein 22 |
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Treatment response Can You Add Charts or Stats?Definitely! Our writers can include data analysis or visuals—charts, graphs—making your paper sharp and evidence-rich. |
Plasminogen activator inhibitor (PAI-1) |
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Grading, treatment planning |
Prostate-specific antigen (PSA) |
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Diagnosis, treatment response, disease recurrence |
Thyroglobulin |
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Treatment response, disease recurrence |
Urokinase plasminogen activator (uPA) |
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Grading, treatment planning |
Cancer markers can help with the diagnosis and treatment of cancer and can give access to targeted therapies.
Cancer markers, genetic markers, diagnostic markers, drug target markers
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Checked Sep 2014
CIGNPOST: KNOWN MARKERS AND WHAT THEY MEAN FOR TREATMENT© Cignpost Ltd 2014PAGE | 1
[EB1]If these are genes not proteins then they should be in italics
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